Changes in version 0.2.1 (2023-11-27) This is a minor release Bi-Bi Reactions A new function bibi() has been added. This function allows to discriminate between sequential and ping-pong mechanisms and estimates the kinetic parameters of enzyme-catalyzed Bi-Bi reactions. Fitting the Michaelis-Menten Model Vignette Equations (3) and (4) in this vignette were originally incomplete. Now, they have been corrected.